Monday, July 1, 2024

Time Event (+)
12:00 - 14:20 Participant Sign-In - Accueil des participants  
14:20 - 14:30 Welcoming words  
14:30 - 16:45 Mucociliary Biology (Neurocampus) (+)  
14:30 - 14:50 › Introduction into mucociliary biology in Xenopus - Laurent KODJABACHIAN, IBDM - Peter Walentek, Universität's Klinikum  
14:50 - 15:05 › SUV4-20H1/KMT5b regulates Xenopus multiciliogenesis - Janet Tait, BMC Munich, Molecular Biology  
15:05 - 15:20 › A workflow to observe single-cell morphogenetic features of developing Xenopus mucociliary epidermis - Mari Tolonen, Novo Nordisk Center for Stem Cell Medicine  
15:20 - 15:40 › Xenopus as a model for the ultra-rare condition, Alstrӧm Syndrome - Charlotte Softley, Softley lab  
15:40 - 16:00 › Deciphering Deuterosome composition to understand sizing of ciliary function in MCCs - Camille Boutin, IBDM, UMR7288  
16:00 - 16:15 › R-Spondin 2 governs Xenopus left-right body axis formation by establishing an FGF signaling gradient - Hyeyoon Lee, German Cancer Research Center  
16:15 - 16:30 › The Xenopus tadpole as a model for mucin biology - Emma Hilton, University of Manchester  
16:30 - 16:45 › Calcium signals shape the apical actin network of multiciliated cells through myosin and RhoA - Max Bergen, University Freiburg Medical Center  
16:45 - 17:10 Break (soft drinks)  
17:10 - 17:55 Keynote (Neurocampus) - Kris Vleminckx (+)  
17:10 - 17:55 › A decade of CRISPR-mediated disease modeling in Xenopus tropicalis, a time to reflect and look forward - Kris Vleminckx, Department of Biomedical Molecular Biology, Ghent University, Cancer Research Institute Ghent  
17:55 - 20:00 Session 1 (Neurocampus) - to be defined (+)  
17:55 - 18:15 › Transcriptional control of early nephrogenesis - Soeren Lienkamp, Institute of Anatomy, University of Zurich, Zurich  
18:15 - 18:35 › Getting your eye in shape: A role for miR-204-1 in eye development - Grant Wheeler, University of East Anglia  
18:35 - 18:50 › The endocytic receptor Lrp2 orchestrates apical constriction and cell polarity to drive cranial neural tube closure - Josefine Hoeren, University of Hohenheim, Institute of Biology, Dept. Zoology  
18:50 - 19:05 › An Investigation into the Effect of Different Strain Rates on the Mechanical and Geometric Properties of Xenopus laevis Epithelia and the Role of Membrane Tension as a Mechanism in Mechnaotransduction - Iona Norwood, Division of Cell Matrix Biology and Regenerative Medicine  
19:05 - 19:20 › Drp1, a regulator of mitochondrial fission, affects Xenopus tail regeneration - Susanne Önel, Philipps Universität Marburg = Philipps University of Marburg  
19:20 - 19:35 › Mechanics of gastrulation: The cellular and biophysical basis of mesoderm intercalation. - Francois Fagotto, CRBM-UniMontpellier-CNRS-UMR5237 - Artur Ruppel, CRBM-UniMontpellier-CNRS-UMR5237  
19:35 - 19:55 › (Phospho)-proteomics of oocyte meiotic division - Leon Peshkin, Harvard Medical School  
20:00 - 21:30 Wines and cheeses... or just cheeses  

Tuesday, July 2, 2024

Time Event (+)
08:45 - 10:30 Session 2 (Neurocampus) - to be defined (+)  
08:45 - 09:05 › Wnt signalling-controlled Gene Regulatory Networks in early Xenopus embryonic development. - Stefan Hoppler, University of Aberdeen, Institute of Medical Sciences  
09:05 - 09:25 › Prdm12 in nociceptor specification and nociception: what the mouse and frog have told us - Eric Bellefroid, Universite Libre de Bruxelles  
09:25 - 09:45 › A retinoic acid-RFX6-Wnt regulatory network patterns the developing digestive system: implications for understanding Mitchell-Riley syndrome. - Aaron Zorn, Division of Developmental Biology and the Center for Stem Cell and Organoid Medicine (CuSTOM), Cincinnati Children's Hospital  
09:45 - 10:00 › CRISPR/Cas9-mediated disruption of an evolutionarily conserved enhancer in the mab21l2 locus induces disease related anomalies in eye morphogenesis in Xenopus tropicalis - Munevver Burcu Cicekdal, Department of Biomedical Molecular Biology, Ghent University, Center for Medical Genetics and Department of Biomolecular Medicine, Ghent University and, Ghent University Hospital  
10:00 - 10:15 › Mechanical regulation of cell division orientation: investigating the role of nuclear mitotic apparatus protein - Nawseen Tarannum, University of Manchester  
10:15 - 10:20 Sponsor  
10:20 - 10:50 Coffee break  
10:50 - 12:35 Session 3 (Neurocampus) - to be defined (+)  
10:50 - 11:10 › Polyploidy in Xenopus lowers metabolic rate by decreasing total cell surface area - Clotilde Cadart, Institut Cochin  
11:10 - 11:30 › Using Xenopus to unpick how mechanical force regulates cell division in complex tissue environments - Sarah Woolner, University of Manchester  
11:30 - 11:45 › XPC-Deficient Xenopus Embryos: An In Vivo Model System for Studying the Mechanisms Underlying Pigmentary Abnormalities in XPC Patients - Joudi El Mir, University of Bordeaux  
11:45 - 12:00 › Deciphering the Mechanisms Behind the Immunologically Cold Phenotype of Wnt-Positive Desmoid Tumors - Marthe Boelens, Cancer Research Institute Ghent (GRIG), Ghent, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium  
12:00 - 12:15 › Establishment of a framework to study and interfere with Xenopus laevis spermatogenesis - Florian Berger, Team 2 : Cell and gene engineering in tolerance, fertility and regenerative medicine  
12:15 - 12:20 ALS_husbandry - Sponsor  
12:30 - 14:30 POSTER - LUNCH AND POSTER SESSION  
14:30 - 15:15 Workshop_1 - Animal ressources and husbandry (+)  
14:30 - 14:50 › European Xenopus Resource Centre Update - Matt Guille, European Xenopus Resource Centre and XenMD, Portsmouth  
15:15 - 16:40 Session 4 - To be defined (+)  
15:15 - 15:35 › Role of nonclassical MHC-Ib and innate-like T cells in Xenopus tadpole immunity - Jacques Robert, University of Rochester Medical Center  
15:35 - 15:55 › The Xenopus Eleuthero-embryonic Thyroid Assay (XETA): Applications in Ecotoxicology for Identifying Thyroid-Active Chemicals - David Du Pasquier, WatchFrog  
15:55 - 16:10 › Histone Acetylation: A Barrier to Cell Fate Reprogramming - Ana Janeva, Helmholtz Munich, Institute of Epigenetics and Stem Cells  
16:10 - 16:25 › Investigating mechanisms of cyst formation in a Xenopus model for autosomal dominant polycystic kidney disease (ADPKD) - Taiyo Yamamoto, University of Zurich  
16:25 - 16:50 Coffee break  
16:50 - 18:00 Session 4 - TBD (+)  
16:50 - 17:05 › Maintenance of H3K4me3 in early Xenopus laevis embryos is indicative of the developmental gene expression program - Oak Meghana, Helmholtz Zentrum, Institute of Epigenetics and Stem Cells  
17:05 - 17:20 › Predictable and precise CRISPR/Cas9-mediated integration - Thomas Naert, University of Ghent  
17:20 - 17:35 › Activation of neural stem cells: NOX signaling effects in the Xenopus retina - Cinthia Violeta Hernandez Puente, Université Paris-Saclay, Institut des Neurosciences Paris-Saclay - NeuroPSI CNRS  
17:35 - 18:30 Transfer to city Center  
18:30 - 20:00 Conférence grand public en Français - Jean Secondi - Jean Secondi  
18:30 - 20:00 Keynote (Pole Juridique et Judiciaire de Pey Berland) (+)  
18:30 - 20:00 › Le monde mal connu et menaçé des amphibiens - Jean Secondi, UMR CNRS 5023 Laboratoire d'écologie des hydrosystèmes naturels et anthropisés, Université d'Angers  

Wednesday, July 3, 2024

Time Event (+)
09:00 - 09:45 Keynote - Maximina Yun (+)  
09:00 - 09:45 › The salamander thymus, a new paradigm of regeneration and anti-ageing - Max Yun, CRTD-Center for Regenerative Therapies Dresden  
09:45 - 10:40 Neurobiology - Denis Combes (+)  
09:45 - 10:05 › Deciphering Early Neural Crest Patterning at a single cell resolution - Anne-Hélène Monsoro-Burq, Institut Curie  
10:05 - 10:25 › The chemo-mechanical regulation of neuronal growth in the developing Xenopus laevis brain - Kristian Franze, Max Planck Zentrum für Physik und Medizin  
10:25 - 10:40 › Inhibition acts as a conductor of vestibulospinal reflex in postural control - Léandre Lavenu, Insitut des Neurosciences Cognitives et Intégratives d'Aquitaine  
10:40 - 11:05 Coffee break  
11:05 - 12:00 Neurobiology - Denis Combes (+)  
11:05 - 11:25 › Animal caps: the Xenopus gastruloids perfect for mechanobiology of induction - Roberto Mayor, UCL  
11:25 - 11:45 › Maturation in central vestibular neurons during frog metamorphosis: one rule to rule them all... or not - François Lambert, Institut de Neurosciences Cognitives et Intégratives d'Aquitaine, CNRS UMR5287  
11:45 - 12:00 › Optimizing two photon scanning microscopy for in-vivo brain-wide functional imaging in Xenopus Laevis tadpoles - Filip Janiak, University of Sussex  
12:00 - 12:05 Sponsor - Zantiks  
12:30 - 14:30 POSTER - LUNCH AND POSTER SESSION  
14:30 - 15:15 Workshop 2 - Omics - Leon Peshkin, Jean-François Riou  
15:15 - 16:25 Session 6 - TBD (+)  
15:15 - 15:35 › Memory of somatic cell identity affects specific cell differentiation programs in cloned organisms - Eva Hörmanseder, Helmholtz Zentrum München  
15:35 - 15:55 › Marcks and Marcks-like 1 proteins promote spinal cord development and regeneration in Xenopus - Gerhard Schlosser, University of Galway  
15:55 - 16:10 › Investigating the molecular network underlying Wilms' tumor formation using CRISPR multiplexing in Xenopus tropicalis - Arne Christiaens, Department of Biomedical Molecular Biology, Ghent University, Cancer Research Institute Ghent  
16:10 - 16:25 › Sox9 and Sox10 regulate different target genes during neural crest and placode development - Merin Lawrence, University of Galway - Gerhard Schlosser, University of Galway  
16:25 - 16:50 Coffee Break  
16:40 - 18:30 Session 7 - TBD (+)  
16:50 - 17:10 › Regulation of the spatiotemporal DNA replication program in early Xenopus laevis embryos - Kathrin Marheineke, Institut Jacques Monod, UMR 7592  
17:10 - 17:30 › Counting Oocyte Divisions: The cyclin B symphony - Aude Dupré, Institute Jacques Monod  
17:30 - 17:50 › Expansion microscopy of Xenopus egg extract spindles - Romain Gibeaux, Institut de Génétique et Développement de Rennes  
17:50 - 18:10 › Oocytes maintain ROS-free mitochondrial metabolism by suppressing complex I - Aida Rodríguez-Nuevo, Centre for Genomic Regulation - Centre de Regulació Genòmica [Barcelona]  
18:10 - 18:25 › Xenopus Modelling Disease (XenMD): Modelling rare monogenic human disease in Xenopus. - Annie Godwin, European Xenopus Resource Centre - XenMD, Portsmouth  
18:25 - 18:40 Closing remarks and Prizes - presentation and poster prizes  
18:40 - 19:30 Free time  
20:00 - 23:55 Closing Gala- Le Café Maritime